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Factors Affecting Fatigue in Breast Cancer Patients Undergoing Radiotherapy

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KMID : 0388320240310010029
Ȳ¼ö¿µ ( Hwang Su-Young ) - 

±Ç¼ÒÈñ ( Kwon So-Hi ) - 

Abstract

Purpose: The aim of this study was to investigate the effects of nutrition risk, physical activity, insomnia, anxiety, anddepression on fatigue among breast cancer patients undergoing radiotherapy.

Methods: The participants of this studywere 160 breast cancer patients at Yeungnam University Medical Center in South Korea. The data were collectedfrom September to November 2022 and analyzed using descriptive statistics, the t-test, analysis of variance, theMann-Whitney test, the Kruskal-Wallis test, the Bonferroni correction, Pearson correlation coefficients, and multipleregression with SPSS version 28.0.

Results: The mean fatigue score was 18.44¡¾7.30 points, while the scores fornutrition risk, insomnia, anxiety, and depression were 2.03¡¾1.52, 5.43¡¾4.79, 6.79¡¾2.81, and 8.17¡¾3.36 points,respectively. Physical activity was measured at 1366.49¡¾1617.87 METs. The general characteristics of theparticipants showed significant differences in fatigue concerning pain (F=13.97, p=.001), duration of illness (t=-2.37,p=.019), and total radiation dose (t=-2.13, p=.035). Fatigue exhibited significant positive correlations with nutritionrisk (r=.35, p<.001), insomnia (r=.35, p<.001), and anxiety (r=.35, p<.001), and a significant negative correlationwith physical activity (r=-.20, p=.012). In multiple regression analysis, the factors influencing fatigue were identifiedas nutrition risk (¥â=.28, p<.001), duration of illness (¥â=.19, p=.005), depression (¥â=.23, p=.006), total radiation dose(¥â=.19, p=.005), and physical activity (¥â=-.14, p=.036).

Conclusion: This study highlights the importance of addressingnutrition risk and depression in breast cancer patients undergoing radiotherapy. Encouraging physical activity mayalso play a crucial role in managing fatigue in these patients. These findings could guide the development of targetedinterventions to improve the well-being of breast cancer patients during radiotherapy.
KeyWords
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Breast neoplasms, Exercise, Fatigue, Nutritional status, Radiotherapy
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